Comment
Author: Admin | 2025-04-28
Procedure (e.g., iridectomy) if they are susceptible. Importance of avoiding concomitant therapy with preparations containing bupropion for use as an adjunct in smoking cessation and preparations used for treatment of major depressive disorder or seasonal affective disorder. May impair patient's ability to perform tasks requiring judgment or motor and cognitive skills. Advise patients to avoid operating machinery or driving a motor vehicle until the effects on the individual are known. May decrease alcohol tolerance. Importance of minimizing or avoiding consumption of alcohol; excessive use of alcohol or abrupt cessation of use may alter the seizure threshold. Importance of informing patients that the shell of certain extended-release tablets (e.g., Aplenzin, Wellbutrin XL) does not dissolve and may be passed in the stool. Advise patients that bupropion hydrochloride extended-release tablets (e.g., Wellbutrin SR) may have an odor. Importance of patients informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as concomitant illnesses. Importance of women notifying clinicians if they are or plan to become pregnant or plan to breast-feed. Advise patients of any pregnancy exposure registry that monitors pregnancy outcomes in women exposed to bupropion during pregnancy. Advise patients that bupropion in distributed into milk in small amounts.Importance of informing patients of other important precautionary information. Additional InformationThe American Society of Health-System Pharmacists, Inc. represents that the information provided in the accompanying monograph was formulated with a reasonable standard of care, and in conformity with professional standards in the field. Readers are advised that decisions regarding use of drugs are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and that the information contained in the monograph is provided for informational purposes only. The manufacturer’s labeling should be consulted for more detailed information. The American Society
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