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Author: Admin | 2025-04-28
PP were 17:2 AE 7:17, 15:4 AE 6:49 and 14:1 AE 6:56, respectively. The difference between AY and PP was statistically signi®cant (p 0:006). When strati®ed according to baseline scores over 14, those patients with mild to moderate MED had a better Erectile Function Domain response to treatment (AY 22:2 AE 4:99, YP 18:2 AE 5:59, PP 16:9 AE 6:91, respectively) than those with scores 14 and below (AY 12:4 AE 5:48, YP 12:7 AE 6:25, PP 11:4 AE 5:02, respectively). Investigators' and patients' assessment of ef®cacy was signi®cantly improved by YP over PP.Chapter 7Oral drug treatment of erectile dysfunctionInternational Journal of Impotence Research, 2003Epidemiological studies have shown the clear preference of patients with erectile dysfunction (ED) for oral treatment. 1 That therapeutic option has proven to be safe and effective in the past 4 y. A large number of oral pharmacological agents have been proposed for the management of ED, some with no satisfactory results, some highly effective and others still in the investigation phase. Those medications are approached according to their pharmacological classification, action mechanism and published results from clinical trials. Oral drugs for ED DRUGS OF CENTRAL AND PERIPHERAL ACTION Adrenergic antagonists Phentolamine and yohimbine Serotonergic agonists Trazodone DRUGS OF PERIPHERAL ACTIONTranscutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trialInternational Journal of Impotence Research, 1999Transcutaneous nitroglycerine has previously been reported to be effective in the treatment of erectile dysfunction. We present our results with the drug in a randomised, placebo controlled, double-blind crossover study. The effect of the drug has been evaluated both under laboratory conditions and in a home study. Eighteen men were included in the study. No effect of nitroglycerine could be demonstrated under laboratory conditions by application of the Rigiscan Monitor. In the home study there was no statistical significant effect of transcutaneous nitroglycerine compared to placebo (P= 0.2813).Yohimbine: a clinical reviewPharmacology & Therapeutics, 2001Although yohimbine (YOH) has been available for the treatment of male erectile dysfunction (ED) for longer than Viagra 1 , there is a perception that little is known about the clinical performance of the drug. This
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