Comment
Author: Admin | 2025-04-28
V. Dosing: Carvedilol Regular Release or Immediate Release (Coreg) Stable Congestive Heart FailureStart: 3.125 mg orally twice daily with foodTitrate up by doubling dose every 2 weeksMaximum doseWeight Weight >85 kg: 50 mg twice daily LV Dysfunction following Myocardial InfarctionStart: 6.25 mg orally twice daily with foodStart 3.125 mg twice daily if lower Heart Rate or Blood PressureTitrate up by doubling dose every 2 weeksTarget: 25 mg orally twice dailyContinue for up to 3 years after Myocardial Infarction Hypertension Start: 6.25 orally twice daily with food Double dose as needed every 7-14 days to maximum of 25 mg orally twice daily Conversion from prior Beta BlockerNo overlap from Metoprolol 50 mg or Atenolol 50 mgStart Carvedilol 6.25 mg bid and increase as aboveOverlap from Atenolol 50-150 or Metoprolol 100-200Add Carvedilol 3.125 mg bid for 2 weeksRaise Carvedilol and lower other Beta BlockerDouble Carvedilol every two weeksReduce Atenolol or Metoprolol by 50 mg every 2 weeksWhen to stop other Beta BlockerAfter 2 weeks on Metoprolol 50 mg orAfter 2 weeks on Atenolol 25 mgReferenceAbraham (2003) Congest Heart Fail 9:251-8 [PubMed] VI. Dosing: Carvedilol Phosphate Sustained Release or Extended Release (Coreg CR) Stable Congestive Heart FailureStart: 10 mg orally dailyTitrate up by doubling dose every 2 weeks as neededMaximum dose: 80 mg/day LV Dysfunction following Myocardial InfarctionStart: 20 mg mg orally once dailyStart 10 mg orally daily if lower Heart Rate or Blood PressureTitrate up by doubling dose every 2 weeks as neededTarget dose: 80 mg/dayContinue for up to 3 years after Myocardial Infarction Hypertension Start: 20 mg orally daily Titrate up by doubling dose every 2 weeks as needed Maximum dose: 80 mg/day Conversion from regular release CarvedilolStart with Coreg CR 20 mg daily when patient takes Immediate Release 12.5 mg twice dailyStart with Coreg CR 40 mg daily when patient takes Immediate Release 25 mg twice daily
Add Comment