Brain tumor drugs

An experimental brain cancer vaccine improved survival time in patients with glioblastoma, the deadliest type of brain tumor. But these drugs are far less effective for brain tumors, because

The blood-brain barrier makes it hard for chemotherapy drugs to affect the tumors. CED allows the drug to reach the tumor directly. Electric

2. Challenges in developing drugs for brain cancer. Compared with peripheral tumors, the treatment of brain tumors faces many challenges (Figure 1).On the one hand, the physiological barriers (such as blood-brain barrier (BBB), blood-brain tumor barrier (BBTB)) and the over-expressed efflux pumps prevent drugs from entering the central nervous system (CNS) and reaching the tumor site.

Several drugs have now been shown to extend patients' lives and improve the management of brain tumors. The Brain Tumor Center at Memorial Sloan Kettering is

Chemotherapy entails the use of specific drugs to treat brain tumors. A cancer specialist may recommend these drugs for malignant tumors that

However, many chemotherapy drugs cannot enter the brain and reach tumor cells. For some brain tumors, medication may be given directly into the

Several drugs have now been shown to extend patients' lives and improve the management of brain tumors. The Brain Tumor Center at Memorial Sloan Kettering is

2. Challenges in developing drugs for brain cancer. Compared with peripheral tumors, the treatment of brain tumors faces many challenges (Figure 1).On the one hand, the physiological barriers (such as blood-brain barrier (BBB), blood-brain tumor barrier (BBTB)) and the over-expressed efflux pumps prevent drugs from entering the central nervous system (CNS) and reaching the tumor site.

The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the BBB and, consequently, survival outcomes for malignant brain tumors