WarfarinPPIs can occasionally enhance the effects of warfarin. The warfarin if omeprazole, pantoprazole, or esomeprazole is started or stopped.
The interaction of omeprazole with warfarin was attributed to a stereoselective inhibition of the hepatic metabolism of the less potent (R)-warfarin
Combined use of warfarin with omeprazole or esomeprazole can potentially enhance the anticoagulant effect of warfarin possibly as a result of
omeprazole (Prilosec)†,, can increase the risk of side effects from omeprazole. warfarin (Jantoven),, can make warfarin less effective. To
Clinically observed warfarin-omeprazole interaction has been found to be associated with the inhibition of R-warfarin hydroxylation by omeprazole. The
Which drugs interact with omeprazole? Warfarin: Abnormal bleeding could result from mixing omeprazole and warfarin, a medication that prevents
The Summary of Product Characteristics (SPC) for warfarin lists omeprazole as a medication that can enhance the anticoagulant effect of warfarin
Combined use of warfarin with omeprazole or esomeprazole can potentially enhance the anticoagulant effect of warfarin possibly as a result of
Omeprazole and Warfarin Warfarin is an anti-clotting drug (or anticoagulant) used to lower the risk of blood clots. Taking omeprazole in combination with warfarin may jeopardize blood coagulation and lead to abnormal bleeding and even death.
Hence Omeprazole being a much more expensive drug than it is now.....