Methadone po to iv

1pt fentanyl IV ≈ mg hydromorphone IV ≈ mg hydromorphone po strategy using buprenorphine and methadone versus conventional methadone maintenance

Butorphanol (IM/IV): 2.0 Codeine (IM/IV): 120 Codeine (PO): 200 Fentanyl (IM/IV): 0.1 Fentanyl (Transdermal): 0.2 Hydrocodone (PO): 30 Hydromorphone (IV/IM/SC): 1.5 Hydromorphone (PO): 7.5 Levorphanol (acute PO): 4.0 Levorphanol (chronic PO): 1.0 Meperidine (IV/IM/SC): 75: Meperidine (PO): 300 Methadone (acute IV): 5.0 Methadone (acute PO): 10

IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Current Infusion Dose Recommended Scheduled Dosing PRN Dosing Midazolam Drip IV Lorazepam (Max Dose: 4 mg) PRN IV Lorazepam (Max Dose: 4 mg)

HYDROmorphone mg(IM/IV/SC), HYDROmorphone mg(PO), Kapanol mg(PO), Morphine Methadone: Dose conversion to/from other opioids and methadone is complex

Oxycodone mg(PO), Oxycodone mg(SC/IV), OxyCONTIN mg(PO), OxyNORM mg(PO) Methadone: Dose conversion to/from other opioids and methadone is complex

How would you replace it? – Equianalgesic: Morphine 30mg PO = Dilaudid 1.5mg IV – Methadone 8 mg PO = Methadone X mg PO IV. Morphine 1mg PO Morphine

IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Benzodiazepines: Lorazepam IV : PO = 1 : 1 Lorazepam Intermittent Dosing at Intervals Other Than Q4H Should be Converted to Q4H Equivalents (Calculator will do this automatically).

Hydromorphone (IV/IM/SC): 1.5 Hydromorphone (PO): 7.5 Levorphanol (acute PO): 4.0 Levorphanol (chronic PO): 1.0 Meperidine (IV/IM/SC): 75: Meperidine (PO): 300 Methadone (acute IV): 5.0 Methadone (acute PO): 10 Methadone (chronic PO): see table above Morphine (IV/IM/SC): 10 Morphine (acute PO): 60 Morphine (chronic PO): 30 Nalbuphine (IV/IM/SC

IV to PO Conversion: Hydromorphone IV : PO = 1 : 5; Methadone IV : PO = 1 : 0.7. Current Infusion Dose Recommended Scheduled Dosing PRN Dosing Midazolam Drip IV Lorazepam (Max Dose: 4 mg) PRN IV Lorazepam (Max Dose: 4 mg)