Formaldehyde in drugs

formaldehyde, which is in many fabrics, especially Common drug allergies include penicillin, other antibiotics, and sulfa drugs.

Most formaldehyde exposures occur by inhalation or by skin/eye contact. Formaldehyde vapor is readily absorbed from the lungs. In cases of acute exposure

In addition, formaldehyde is known to cross-link gelatin capsule shells, leading to dissolution slowdown and incomplete drug release. The cross-linking is a result of formaldehyde interaction with amino groups in gelatin to form an insoluble protein. Formaldehyde is susceptible to air oxidation and could be partially converted to formic acid.

Formaldehyde (gas) is on the Proposition 65 list because it can cause cancer. Exposure to formaldehyde can cause leukemia and cancers of the nose, throat

Formaldehyde in these excipients reacted with the drug substance BMS- and formed a hydroxymethyl derivative in the parenteral formulation (Fig. 3.2). Trace level of formaldehyde (8 ppm) in BMS- formulation (10 mg/mL) was sufficient to generate 1 % degradation product.

Compared with the amounts of formaldehyde analyzed from the 0.2% formaldehyde donors, the results obtained by acetylacetone method were 1.62~

Formaldehyde. Formaldehyde is a cold sterilant that effectively kills all microorganisms, including spores and resistant viruses, when used in proper concentrations and given adequate contact time. There are several reports of serious to deadly septicemia, with inadequate formaldehyde concentrations being used to disinfect the fluid path of

Products containing formaldehyde: formaldehyde topical. Brand names: Formadon, Lazerformalyde, Forma-Ray, Formalyde-10 Spray, Formalaz.

Formaldehyde is a Standardized Chemical Allergen. The physiologic effect of formaldehyde is by means of Increased Histamine Release, and Cell-mediated Immunity.