Impact of Amlodipine on Other Drugs . Simvastatin: Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily [see Clinical Pharmacology ( 12.3)] . Immunosuppressants:
amlodipine and simvastatin, 2) amlodipine and another HMG-CoA- reductase inhibitor except simvastatin, and 3) simvastatin without amlodipine
However, there is a drug interaction between simvastatin and amlodipine. Amlodipine can increase the concentration of simvastatin which
Impact of Amlodipine on Other Drugs . Simvastatin: Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily [see Clinical Pharmacology ( 12.3)] . Immunosuppressants:
the drug-drug interaction between amlodipine and simvastatin except simvastatin or patients receiving simvastatin without amlodipine
Amlodipine and Simvastatin Amlodipine and simvastatin are used to treat different things (amlodipine- high blood pressure and simvastatin high cholesterol) and sometimes prescribed together. Taking them together may increase the amount of simvastatin in the blood.
7.2 Impact of Amlodipine on Other Drugs. Simvastatin. Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily [see Clinical Pharmacology (12.3)]. Immunosuppressants
amlodipine simvastatin Applies to: amlodipine, simvastatin. Talk to your doctor before using simvastatin together with amLODIPine. Combining these medications may significantly increase the blood levels of simvastatin.
7.2 Impact of Amlodipine on Other Drugs. Simvastatin Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Limit the dose of simvastatin in patients on amlodipine to 20 mg daily [seeCLINICAL PHARMACOLOGY (12.3)].
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