Moxifloxacinhas some anaerobic coverage while levofloxacin and ciprofloxacin do not. Metronidazole – no longer the 1st choice for C.diff
Ciprofloxacin (prototypical drug); Ofloxacin. 3rd generation: Levofloxacin Pyogenic Liver Abscess for anaerobic coverage); Peritonitis
Would not recommend its use in isolation against infections. Moxifloxacinhas some anaerobic coverage while levofloxacin and ciprofloxacin
cover MRSA, Enterobacteriaceae, Pseudomonas and obligate anaerobes. It does not provide coverage for MRSA or Pseudomonas. What Does Ciprofloxacin Cover?
Fluoroquinolones - Ciprofloxacin (~70% coverage) Levofloxacin (~65%), NOT ANTIBIOTICS WITH ANAEROBE COVERAGE. Infections in which anaerobes are
Enterococcus: Ciprofloxacin has reasonable coverage for Enterococcus faecalis, but often misses Enterococcus faecium. Anaerobic coverage: Only moxifloxacin has anaerobic coverage.
Anaerobic coverage ofloxacin plus metronidazole (91%); doxycycline plus metronidazole (91%) or ciprofloxacin plus tinidazole (96%); azithromycin alone (97%)
Moxifloxacinhas some anaerobic coverage while levofloxacin and ciprofloxacin do not. Metronidazole – no longer the 1st choice for C.diff
ANTIBACTERIALS 1. Ciprofloxacin (PO and IV) Spectrum: best gram negative coverage of FQs, but virtually no gram positive coverage. Lacks good anaerobic
Comments