Max dose of methadone

Max 3 doses in 24hrs. On day 4/5 – doses consolidated. Hold 10mg PRN dose Methadone 40mg PO OD starting dose. Addition of Hydromorphone IR

❑ Give Day 3 max dose. Continue protocol until reaching 60mg daily DO continue methadone or bup dosing before and after surgery.

Bao, A meta-analysis of retention in methadone maintenance by dose and dosing ○ 30mg is max single dose and 40mg is max total daily dose at

Max dose is 300 mg bid. Reduce dose in renal Total daily oral morphine dose. Estimated oral methadone as a % of total daily morphine.

Grapefruit juice. Carbamazepine. Phenytonin. Rifampicin/rifampin. St Methadone 10mg q3h PRN. Max 3 doses in 24hrs. On day 4/5 – doses

Calculate starting lorazepam dose: Midazolam: Multiply current midazolam drip rate (mg/kg/h) X 0.5 = _____ mg/kg lorazepam q6h (max initial dose 0.2 mg/kg/dose q6h AND max 4 mg q6h) Weaning Methadone and Lorazepam Once stable on methadone and/or lorazepam for 24 h with no withdrawal symptoms, wean methadone and lorazepam as follows. Methadone

Methadone 10mg q3h PRN. Max 3 doses in 24hrs. On day 4/5 – doses Methadone 40mg PO OD starting dose. Addition of Hydromorphone IR tablets.

Not recommended for pain in secure environments except when pain emerges when methadone dose is reduced as Max dose 120mg daily. Third Choice.

Methadone. See conversion tools. Hydrocodone. Not Available. 20 MAX BOLUS DOSE. MAX INFUSION RATE. Ropivacaine. 2mon: 4mg/kg. 2mon: 0.3mg/kg