Propofol (Diprivan). Propofol is a hypnotic sedative agent used in both adults and children. Often an anesthesiologist is required to administer propofol and
See Table 1 for context-sensitive half-lives and reversal of common anesthetics. Propofol: Delayed emergence is relatively common after prolonged administration. Extremely rare hepatic enzyme mutations have been reported in in cases of delayed emergence. 3; Reversal agents; Naloxone is used for reversal of opiates.
= Titrate to effect. Induction Agents. Dose. Presentation. Propofol. 2–3 mg Reversal for muscle relaxants. Neostigmine 2.5 mg Glycopyrronium 500 mcg.
by P Grendelmeier 2024 Cited by 60However, unlike the benzodiazepines, propofol does not have a reversal agent. Many specialty bodies recommend its use only by those trained in the
It is common to combine propofol with other drugs (such as a analgesic, sedating, anesthetic, and reversal agents. The law and rules also
by HC Alves 2024 Cited by 50the use of medetomidine/ketamine and its reversal with atipamezole for chemical Kanto JH (2024) Propofol, the newest induction agent of anesthesia
by BW Sipe 2024Methods: 21 patients (pts) presenting for outpatient upper endoscopy were prospectively randomized to 3 arms: multi-drug propofol reversal agents (P R)
Unlike benzodiazepines and opiates, there are no reversal agents for propofol. Hence the ability to manage adverse events such as airway
Propofol is the mostly commonly used parenteral anesthetic agent in the United States, extensively used for minor and outpatient surgical procedures because of its rapid onset and reversal of action, and in intensive care units (ICUs) for maintenance of coma. Propofol has been associated with rare instances of idiosyncratic acute liver injury; in addition, prolonged high dose propofol therapy
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