Glutamate drugs

Glutamate is the chief excitatory neurotransmitter in the mature central nervous system (CNS). Describes the mechanisms with which drugs affect glutamate

The amino and -carboxyl groups of glutamate molecules are known to be required for glutamate binding to various known glutamate-binding proteins/receptors, and are also present in many glutamate

These same receptors are targeted also by drugs like heroin and cocaine. Most importantly, ketamine affects the glutamate system. Glutamate is

glutamate signaling (blue) in the brain. Homeostatic down regulation of glutamate We can then begin to develop ketamine-like drugs without the

Phencyclidine is a hallucinogen and a dissociative drug that interferes with glutamate levels in the brain. Glutamate regulates the perception or feeling of

Glutamate is a chemical messenger that plays an important role in learning and memory. It also helps regulate mood. Learn more. Psychostimulant drug effects on glutamate

by KAB Lapidus 2024 Cited by 123drugs with activity at the metabotropic glutamate receptors (mGluRs). glutamate signaling provides multiple targets of glutamatergic drug

Future treatments may involve drugs that increase H2S levels in the brain Postviral production of antibodies to glutamate receptors, affecting glutamate-gated

Mechanisms of Oxidative Glutamate Toxicity: The Glutamate/Cystine Antiporter System xc¯ as a Neuroprotective Drug Target Medicinal Chemistry of Drugs