The Summary of Product Characteristics (SPC) for warfarin lists omeprazole as a medication that can enhance the anticoagulant effect of warfarin
Warfarin เป็นยาต้านการแข็งตัวของเลือด ใช้ป้องกันการเกิดก้อนเลือดอุดตันในหลอดเลือดแดงและหลอดเลือดดำ จากการสืบค้นข้อมูลพบว่าการใช้ omeprazole อาจเพิ่มระดับยา warfarin ในร่างกายได้
Which drugs interact with omeprazole? Warfarin: Abnormal bleeding could result from mixing omeprazole and warfarin, a medication that prevents
warfarin), CYP3A (midazolam, R-warfarin), CYP2C9 (S-warfarin), CYP2D6 (dextromethorphan), CYP2C19 (omeprazole), and drug transporters, BCRP/OATP1B1/OATP1B3
by Y Liu 2024 Cited by 4Comparing co-administered warfarin and imrecoxib with warfarin alone, for S-warfarin Lack of effect of omeprazole or of an aluminium
Combined use of warfarin with omeprazole or esomeprazole can potentially enhance the anticoagulant effect of warfarin possibly as a result of
by Q Zhou 2024 Cited by 15Abstract: Clinically observed warfarin-omeprazole interaction has been found to be associated with the inhibition of R- warfarin hydroxylation by omeprazole
warfarin), CYP3A (midazolam, R-warfarin), CYP2C9 (S-warfarin), CYP2D6 (dextromethorphan), CYP2C19 (omeprazole), and drug transporters, BCRP/OATP1B1/OATP1B3
Clinically observed warfarin-omeprazole interaction has been found to be associated with the inhibition of R-warfarin hydroxylation by omeprazole. The
Hence Omeprazole being a much more expensive drug than it is now.....