Amantadine withdrawal symptoms

Amantadine (Symmetrel)​​ Though not FDA-approved for ADHD, amantadine's dopamine-enhancing activity may also help improve ADHD symptoms. Research

by KM Kampman 2024 Cited by 99Conclusions: Amantadine may be an effective treatment for cocaine-dependent patients with severe cocaine withdrawal symptoms. (Am J Psychiatry 2024; 152–

What are the adverse effects of Amantadine? Adverse effects or drug interactions in dogs or cats receiving amantadine are uncommon. It is reported that some dogs may develop agitation, vomiting, flatulence, or diarrhoea (which may be watery), particularly in the early days of amantadine therapy. Amantadine can be stopped without a withdrawal

Amantadine should NOT be stopped abruptly if you have been taking it for more than four weeks. What can happen if you stop amantadine abruptly or even reduce your dose rapidly, is that you are at risk of developing serious symptoms that resemble neuroleptic malignant syndrome. What are the symptoms of rapid withdrawal of amantadine?

What are the symptoms of rapid withdrawal of amantadine? agitation. anxiety. delirium. delusions. depression. hallucinations. paranoia. parkinsonian crisis.

We suggest that based on the available data, levodopa, dopamine agonists (DA), and amantadine should not be discontinued abruptly. Abrupt or sudden reduction of DA or amantadine in particular can lead to severe life-threatening withdrawal symptoms. Tapering off levodopa, COMT inhibitors, and MAO-B inhibitors may worsen motor and non-motor symptoms.

As soon as he received the first injection of amantadine sulfate, he was conscious and completely oriented. An amantadine withdrawal syndrome was suspected and an oral amantadine was continued. He did not experience any further psychotic symptoms. He was discharged on oral amantadine [duration of treatment to reaction onset and outcome not stated].

Amantadine significantly improved symptoms of ADHD and was well tolerated. The results of this study suggest that amantadine may be considered

The results are not conclusive for amantadine. Kampman et al. demonstrated that amantadine is more effective than placebo to alleviate the cocaine withdrawal symptoms (19). Other studies showed the efficacy of amantadine in controlling withdrawal symptoms in cocaine-addicted patients as well as decreasing its use (20, 21).