Does amiodarone cause hypotension

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Actual: Renal impairment does not influence the pharmacokinetics of amiodarone. Fentanyl (CYP3A4 substrate) in combination with amiodarone may cause hypotension.
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Amiodarone can cause bradycardia and hypotension in some patients. One unique thing about amiodarone is it's very long half-life of up to 40 days. One key concept again with using amiodarone is its potential for bradycardia and hypotension. Adenosine like amiodarone is an antiarrhythmic drug.

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Amiodarone can still lead to hypotension initially, especially when bolused; Afib with RVR is unlikely to be the cause of hypotension alone

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Evidence has shown that Amiodarone does have the potential to cause Bradycardia and Hypotension, and can cause the patient to rearrest more rapidly.

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Other reported interactions with amiodarone: Fentanyl (CYP3A4 substrate) in combination with amiodarone may cause hypotension, bradycardia, and decreased

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Fentanyl In combination with amiodarone may cause hypotension, bradycardia, and decreased cardiac output. Grapefruit juice Amiodarone plasma

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The second-line drug amiodarone was given to the patient for rate control. He developed severe hypotension related to amiodarone and required inotropic support along with rapid-sequence intubation. Conclusions: Intravenous amiodarone can cause severe and refractory hypotension.

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Amiodarone can still lead to hypotension initially, especially when bolused; Afib with RVR is unlikely to be the cause of hypotension alone

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by JL Merino Cited by 8Finally, amiodarone may cause hypotension in approximately 15% of patients receiving it intravenously. Hypotension can be treated initially by

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CONCLUSIONS: Intravenous amiodarone can cause severe and refractory hypotension. Keywords: Amiodarone - adverse effects, Anti-Arrhythmia Agents

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